› Short loop-length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites - Alain Nicolas, Institut Curie, Paris, France
08:30-08:50 (20min)
› Evidence that G-quadruplex levels increase during S-phase in human cells, and are elevated throughout the cell cycle in Werner and Bloom syndrome cells - F. Brad Johnson, University of Pennsylvania, USA
08:50-09:10 (20min)
› Recognition of unique RNA structures by quadruplex helicases and their functional consequences. - Sean McKenna, University of Manitoba, Canada
09:10-09:30 (20min)
› G4 elements and DNA replication origins: a genome-wide and functional analysis in metazoans - Paulina Prorok, Institut de Génétique Humaine, CNRS, Montpellier, France
09:30-09:50 (20min)
› G4 motifs are necessary but not sufficient for replication initiation in Vertebrates - Marie-Noëlle Prioleau, Institut Jacques Monod, Université Paris Diderot, Paris, France
09:50-10:10 (20min)
› Propagation of a single unresolved G quadruplex structure in proliferating tissues causes multiple genomic rearrangements and genetic heterogeneity - Marcel Tijsterman, Leiden University Medical Center, Leiden, The Netherlands
10:10-10:30 (20min)
› Encapsulation and Delivery of Therapeutic Agents by Nanoparticles Formed Supramolecular G-quadruplexes - Jose Rivera, University of Puerto Rico, Río Piedras, Puerto Rico
11:00-11:20 (20min)
› Intramolecular, Multimeric and Supramolecular G-quadruplex Assemblies - Viktor Viglasky, Pavol Jozef Safarik University, Kosice, Slovakia
11:20-11:40 (20min)
› Stabilising i-motif DNA structures with cations and ligands - Zoe Waller, UEA School of Pharmacy, Norwich, UK
11:40-12:00 (20min)
› The Quest for Charge Transport in single Adsorbed Long DNA-Based Molecules - Danny Porath, Institute of Chemistry and Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, 91904
12:00-12:20 (20min)
› DNA G-quadruplex formation: a new pathway - Primoz Sket, EN-FIST Centre of Excellence, Slovenian NMR Centre, National Institute of Chemistry, Ljubljana, Slovenia
12:20-12:25 (05min)
› Thermodynamics and kinetics study of individual K+ binding events reveal new aspects of DNA G-quadruplex folding pathways - Adrien Marchand, Inserm U869 ARNA, IECB, Bordeaux, France
12:25-12:30 (05min)
› Electronic Properties of Guanine Assemblies in G-quadruplex Nucleic Acids - Christopher Lech, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore
12:30-12:35 (05min)
› G-quartets and Supramolecular Structures of Guanosine-5'-monophosphates: Effect of the Ribose versus 2'-deoxyribose Residue - Katerina Mudronova, Faculty of Mathematics and Physics, Praha/Prague, Czech Republic
12:35-12:40 (05min)
› G-quadruplex DNAzyme-modified Nucleotides for diagnostic applications - Daniela Verga, University of Konstanz, Germany
12:40-12:45 (05min)
› Higher-Order Human Telomeric G-Quadruplex DNA Metalloenzymes Enhance Enantioselectivity in the Diels–Alder Reaction - Yinghao Li, University of Chinese Academy of Sciences, State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, P.R. China
12:45-12:50 (05min)
› G4-hunter, a novel algorithm to predict G-quadruplex folding propensity through score computing - Amina Bedrat, U869, Laboratoire ARNA, IECB, Bordeaux, France
12:50-12:55 (05min)
› Interaction of mutant p53 proteins with DNA quadruplexes in vitro and in cells - Marie Brázdová, Institute of Biophysics of the AS CR, v.v.i., Brno, Czech Republic
12:55-13:00 (05min)
› Role of Nucleotide Excision Repair and Topoisomerase II proteins on pyridostatin-induced double-stranded DNA breaks - Charlotte Dunet, Institut de pharmacologie et de biologie structurale, CNRS, Toulouse, France
13:00-13:05 (05min)
› G4s and RecQ helicases in the human malaria parasite Plasmodium falciparum - Lynne Harris, Keele University, UK
13:05-13:10 (05min)
› A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands. - Anne Bourdoncle, ARNA Laboratory, Bordeaux, France
13:10-15:40 (2h30)
› A Naphthalene Diimide Dyad as Selective Light Up Probe for G-quadruplex Sensing - Filippo Doria, Department of Chemistry, University of Pavia
13:10-15:40 (2h30)
› Design and synthesis of a berberine dimer as a fluorescent ligand with high affinity toward G-quadruplex - Masayuki Tera, Suntory Foundation for Life Science, Osaka, Japan
13:10-15:40 (2h30)
› Effect of low molecular weight ligands on the structural stability of G-quadruplexes - Petra Krafčíková, University of P.J. Safarik, Košice, Slovak Republic
13:10-15:40 (2h30)
› Extended core naphtalene diimides as G-quadruplex sensors and improved anticancer compounds - Matteo Nadai, Department of Molecular Medicine, University of Padua
13:10-15:40 (2h30)
› FRET-melting studies to assess the selectivity of G4 ligands - Aurore De Rache, ARNA Laboratory, IECB Bordeaux, France
13:10-15:40 (2h30)
› G-quadruplex structure alteration induced by cations in relation to DNAzyme peroxidase activity - Joanna Kosman, Laboratory of Bioanalytical Chemistry, Faculty of Chemistry, Adam Mickiewicz University
13:10-15:40 (2h30)
› Indolylmethyleneindanone based molecules specifically stabilize promoter quadruplex DNAs over telomeric and duplex DNAs - Divesh Kumar K V, Indian Institute of Technology [Bombay] - PRADEEPKUMAR P.I., PRADEEPKUMAR P.I.
13:10-15:40 (2h30)
› Interactions of two pentanuclear lanthanide (III) metallacrowns with human telomeric DNA - Ewa Rajczak, Adam Mickiewicz University, Faculty of Chemistry, Poland
13:10-15:40 (2h30)
› Investigation of the effect of G-quadruplex ligand on the expression and splicing of VEGF mRNA - Taiki Saito, Graduate school of Engineering, Tokyo University of Agriculture and Technology
13:10-15:40 (2h30)
› Light induced conformational changes of the telomeric G4 DNA in complex with Zn(II) tetracarboxymethyl porphyrin - Artemy Beniaminov, Engelhardt Institute of Molecular Biology RAS, Moscow, Russia
13:10-15:40 (2h30)
› Small Molecule Destabilisation of Intermolecular G-Quadruplexes - Louis Chan, Department of Chemistry (Cambridge, UK)
13:10-15:40 (2h30)
› Targeting DNA quadruplexes with aromatic oligoamide foldamers - Simon Dawson, Chimie et Biologie des Membranes et des Nanoobjets
13:10-15:40 (2h30)
› Terpyridine-platinum complexes derivatives as probes for telomere targeting - Sophie Bombard, INSERM UMR-S 1007, Université Paris Descartes;
13:10-15:40 (2h30)
› Base Lesions in the G-tetrads and the Loops Have Varying Effects on the Folding and Stability of the Human Telomere G-quadruplex - Helena Konvalinová, Department of Biochemistry, Faculty of Science, Masaryk University
13:15-15:40 (2h25)
› Divalent cations prefold a telomeric G-Quadruplex sequence into a nascent, parallel structural form - Patrick Groves, University of Gdansk, Instituto de Tecnologia Química e Biológica
13:15-15:40 (2h25)
› Effective incorporation of modified nucleotides into G-quadruplex nucleic acids - Brahim Heddi, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore
13:15-15:40 (2h25)
› Gene regulation by RNA G-quadruplexes. New insights into the G-quadruplex structure at the 5'UTR of the BCL2 mRNA human proto-oncogene - Alicia Dominguez-Martin, University of Zürich
13:15-15:40 (2h25)
› Insights from 10 µs-scale molecular dynamics simulations of human telomeric quadruplex - Barira Islam, Central European Institute of Technology, Masaryk University
13:15-15:40 (2h25)
› Interaction between guanosine and a G-quadruplex with a vacant site - Si Ming Pang, School of Physical and Mathematical Sciences, NTU
13:15-15:40 (2h25)
› Investigating divalent cation binding to folded G-Quadruplexes - Malgorzata Palczewska, Department of Biomedical Chemistry, University of Gdansk, POLAND
13:15-15:40 (2h25)
› Joining of Multiple Duplex Stems at a Single Quadruplex Loop - Kah Wai Lim, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore
13:15-15:40 (2h25)
› Probing the folding dynamics of human telomeric G-quadruplex with single-molecule FRET - Mikayel Aznauryan, Centre for DNA Nanotechnology (CDNA), Aarhus University, Interdisciplinary Nanoscience Center (iNANO), Aarhus University
13:15-15:40 (2h25)
› Structure, stability and cooperativity in guanine quadruplexes - Celia Fonseca Guerra, VU University Amsterdam
13:15-15:40 (2h25)
› Fine-tuning of the DNA i-motif stability: lesson learnt from epigenetic regulation of telomeric DNA from plants - Silvie Trantirkova, Central European Institute of Technology - Masaryk University
13:20-15:40 (2h20)
› Hairpin or i-Motif? - Elise Wright, UEA School of Pharmacy, Norwich, UK
13:20-15:40 (2h20)
› Spectral characterization of i-motif enclosed in a hairpin loop for intracellular pH measurements - Anna Dembska, Faculty of Chemistry, Adam Mickiewicz University, Poznan, Poland
13:20-15:40 (2h20)
› Study of the solution equilibria of two i-motif- and G-quadruplex-forming sequences found at the SMARCA4 gen - Sanae Benabou, Universitat de Barcelona
13:20-15:40 (2h20)
› Discovery of a New Fluorescent Light-Up Probe Specific to Parallel G-Quadruplexes - Shuo-Bin Chen, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou
13:25-15:40 (2h15)
› Duplex stem-loop-containing quadruplex motifs in the human genome: A combined genomic and structural study - Vladimir Kuznetsov, Bioinformatics Institute/A*STAR
13:25-15:40 (2h15)
› Evolutionarily conserved properties of telomeric DNA - Lukas Trantirek, Central European Institute of Technology - Masaryk University
13:25-15:40 (2h15)
› Importance of G4 structure for the activity of metazoan origins of DNA replication - Paulina Prorok, Institut de génétique humaine - Marcel Méchali, Institut de génétique humaine
13:25-15:40 (2h15)
› Short loop length and high thermal stability determine genomic instability induced by G-quadruplex forming minisatellites - Frédéric SAMAZAN, Dynamique de l'information génétique : bases fondamentales et cancer
13:25-15:40 (2h15)
› A dual functional G4-DNAzyme for cells antiproliferation mediated by nucleolin targeting and hydrogen peroxide trigger - Yan Yang, Dalian Institute of Chemical Physics
13:30-15:40 (2h10)
› Molecular Diagnostics Based on Quadruplex Priming Amplification and Nicking Enzyme Activity - Shota Gogichaishvili, Andronikashvili Institute of Physics, TSU, Tbilisi 0177, Republic of Georgia
13:30-15:40 (2h10)
› Thermodynamic and Optical properties of Quadruplex Primers for Isothermal DNA Amplification - David Gvarjaladze, Institute of Biophysics, Ilia State University, Tbilisi 0162, Republic of Georgia
13:35-15:40 (2h05)
› Braf promoter undergoes to “non-canonical”rearrangements under nearly physiological conditions - Maria Laura Greco, Dept. of Pharmaceutical and Pharmacological Sciences, via Marzolo 5,35131, Padova, Italy
13:40-15:40 (2h)
› Comparing p63 to other p53 family members on binding to G4 - Matej Adámik, Institute of Biophysics of the AS CR, v.v.i., Brno, CR
13:40-15:40 (2h)
› G-rich sequences within proto-oncogene KIT promoter region as targets for anticancer therapy - claudia sissi, Department of Pharmaceutical and Pharmacological Sciences, University of Padova
13:40-15:40 (2h)
› Stabilization of the G-quadruplex at the VEGF IRES represses cap-independent translation - Stefania Millevoi, Cancer Research Center of Toulouse (CRCT)
13:40-15:40 (2h)
› The Amyloid Precursor Protein is Negatively Regulated by a 3'UTR G-quadruplex - Ezekiel Crenshaw, Drexel University
13:40-15:40 (2h)
› Investigation of G-quadruplex-ligand interactions using NMR spectroscopy - Julia Wirmer-Bartoschek, J.W. Goethe Universität Frankfurt, Max von Laue Str. 7, 60439 Frankfurt
13:45-15:40 (1h55)
› Fine-tuning molecular tools for probing the G4 genome - Marie-Paule Teulade-Fichou, Institut Curie, Orsay, France
15:40-16:00 (20min)
› Topologies selective small molecules for telemetric G-quadruplex - Kazuo Nagasawa, Tokyo University of Agriculture and Technology, Japan
16:00-16:20 (20min)
› Fluorescent anti-tumor agents (FATAs) induced cancer cell death via the interaction of mitochondrial G-quadruplex DNA - Ta-Chau Chang, Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan
16:20-16:40 (20min)
› Topology Specific Stabilization of Promoter over Telomeric G-Quadruplex DNAs by Designer Molecules - Pradeepkumar P.I., Indian Institute of Technology Bombay, Mumbai, India
16:40-17:00 (20min)
› Photochemistry Gives the Green Light to Tel22 Thymine Targeting - Mauro Freccero, University of Pavia, Italy
17:00-17:20 (20min)
› Quadruplex targeting and imaging: “stay on TASQ!” - David Monchaud, Institut de Chimie Moléculaire de l'Université de Bourgogne, Dijon, France
17:20-17:40 (20min)
› Epigenetic reprogramming with G-quadruplex ligands - Guillaume Guilbaud, MRC Laboratory of Molecular Biology, Cambridge, UK
17:40-18:00 (20min)